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(October 18, 2025) Evaluation of Polmacoxib 2 mg for the Management of Hip and Knee Osteoarthritis: A Prospective, Single-Arm, Multicenter, Open-Label Study

Acknowledgements We thank Marta Pulido, for editing this paper and for editorial assistance

These proteins help maintain proper proteostasis and attenuate endoplasmic reticulum stress, thereby supporting dopaminergic neuron viability [237, 238]

At the transcriptomic level, lactylation-related gene (LRG) signatures built across multiple tumors stratify prognosis and, in some studies, associate with responses to targeted or immune therapies (e.g., HCC, gastric, pancreatic), complementing tissue and serum markers [385, 386]

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